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目的:探讨胰腺实性假乳头状瘤(solid pseudo-papillary tumors of pancreas)的诊断治疗经验。方法:回顾性分析2008年1月至2014年12月在兰州大学第一医院14例SPTP的临床表现、影像学检查、病理结果、治疗及预后。结果:SPTP无特异性临床表现,可为腹部胀痛不适,CT检查可见胰腺部位囊实性或实性占位性病变,14例均行手术治疗,其中胰十二指肠术2例,肿瘤局部切除3例,胰体尾切除2例,胰腺体尾部+脾脏切除3例,胰腺中段切除+胰胃吻合3例,胰颈体尾切除1例。14例肿瘤标本病理结果均具有SPTP的典型病理学表现,随访3个月至5年,均未发现肿瘤复发及转移。结论:SPTP是一种低度恶性肿瘤,治疗以手术为主,手术方式应依据术前CT和术中探查来决定,预后良好。
Objective: To investigate the diagnosis and treatment of solid pseudopapillary tumors of the pancreas. Methods: The clinical manifestations, imaging findings, pathological findings, treatment and prognosis of 14 patients with SPTP in the First Hospital of Lanzhou University from January 2008 to December 2014 were analyzed retrospectively. Results: There was no specific clinical manifestations of SPTP, which could be discomfort of abdominal distension. Computed tomography showed cystic or solid mass lesions of pancreas. All of 14 patients underwent surgical treatment, including 2 cases of pancreatoduodenectomy, Local resection in 3 cases, pancreatic body tail resection in 2 cases, pancreatic body tail + splenic resection in 3 cases, pancreatic resection + pancreaticojejunostomy in 3 cases, pancreatic excision in 1 case. The pathological findings of 14 cases of tumor specimens showed the typical pathological findings of SPTP. No recurrence and metastasis were observed after 3 months to 5 years follow-up. Conclusion: SPTP is a kind of low grade malignant tumor. The treatment is mainly based on the operation. The operation method should be based on preoperative CT and intraoperative exploration, and the prognosis is good.