论文部分内容阅读
应用放射免疫方法和多普勒超声心动图对25例冠心病患者和21例正常人分别测定血浆心钠素(ANF)水平和左室功能.结果显示,冠心病患者血浆ANF显著升高,左室舒张功能均有不同程度的障碍;ANF与反映左室舒张功能的多普勒参数(A/E、AceT/DecT)有一定相关性(分别为r=0.46、r=0.6);与LVEF呈显著负相关(r=-0.61).表明测定冠心病患者血浆ANF水平可以反映心功能的变化,特别是早期舒张功能的障碍.
Plasma atrial natriuretic peptide (ANF) level and left ventricular function were measured by radioimmunoassay and Doppler echocardiography in 25 patients with coronary heart disease and 21 normal subjects.The results showed that plasma ANF was significantly elevated in patients with coronary heart disease and left Diastolic function had different degrees of dysfunction; ANF was related to Doppler parameters (A / E, AceT / DecT) which reflect left ventricular diastolic function (r = 0.46, r = 0.6 respectively) (R = -0.61), indicating that the determination of plasma ANF levels in patients with coronary heart disease can reflect changes in cardiac function, especially in early diastolic dysfunction.