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洛克二阶段随机试验(RCT)的设计和方法,允许治疗的优先选择在临床试验中依据个体化进行评估。为了了解患者的选择对其预后的影响,研究者采用了洛克二阶段随机试验设计和分析方法。
Locke’s two-stage randomized trial (RCT) design and methodology allows prioritized treatment to be assessed on a case-by-case basis in clinical trials. To understand the impact of patient selection on their prognosis, the researchers used Locke’s two-stage randomized trial design and analysis.