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目的探讨ROC曲线对于评价前列腺液中Zn、CRP检测对细菌性前列腺炎的诊断价值。方法收集69例诊断为慢性细菌性前列腺炎患者血液及前列腺标本,分别对血液进行Zn、CRP检测,对前列腺标本进行Zn、CRP及常规镜检。同时以69位健康体检人群作为阴性对照。结果前列腺炎患者前列腺液中Zn水平[(463.93±118.4)μmol/L]明显低于正常对照人群[(765.38±166.28)μmol/L],且与镜检白细胞数量呈负相关(r=-0.408),CRP含量[(14.76±6.06)mg/L]显著高于正常对照人群[(6.03±2.73)mg/L],且与镜检白细胞数量呈正相关(r=0.391)。血液中Zn、CRP与健康对照人群差异未见统计学意义。结论对疑似细菌性前列腺炎患者前列腺标本进行常规镜检及Zn、CRP检测有助于早期诊断,早期治疗。
Objective To investigate the diagnostic value of ROC curve in the diagnosis of bacterial prostatitis by detecting Zn and CRP in prostatic fluid. Methods Blood and prostate samples from 69 patients diagnosed as chronic bacterial prostatitis were collected. Zn and CRP were detected in blood and Zn, CRP and routine microscopic examination of prostate specimens. 69 healthy people at the same time as a negative control group. Results The level of Zn in prostatic fluid of patients with prostatitis [(463.93 ± 118.4) μmol / L] was significantly lower than that of normal controls [(765.38 ± 166.28) μmol / L] and negatively correlated with the number of leukocytes (r = -0.408 ), CRP content [(14.76 ± 6.06) mg / L] was significantly higher than that of the normal control group [(6.03 ± 2.73) mg / L], and positively correlated with the number of microscopic leukocytes (r = 0.391). The difference of Zn and CRP in blood and healthy controls was not statistically significant. Conclusion Conventional microscopic examination and Zn, CRP detection of prostate specimens in patients with suspected bacterial prostatitis are helpful for early diagnosis and early treatment.