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痛风是一种以嘌呤代谢障碍为主的全身性疾病。嘌呤是人体核酸的重要组成成分。体内的嘌呤主要有两个来源,小部分来源于饮食,大部分由体内合成。嘌呤在人体内经过新陈代谢,逐步分解,最后形成尿酸。尿酸主要经肾脏由尿液排出,小部分随粪便排泄。在体液中,尿酸与钠离子相结合,生成尿酸钠,正常情况下,其饱和度为6.8mg/dL。当体内嘌呤产生过多,超过肾脏的排泄能力时,尿酸便积聚于血液和组织中。血液中尿酸水平超出正常时称为高尿酸血症。通常,血尿酸浓度
Gout is a systemic disease predominated by purine metabolism disorders. Purine is an important component of human nucleic acid. There are two main sources of purines in the body, a small part of which comes from the diet, mostly from in vivo synthesis. Purine in the human body through metabolism, and gradually decomposition, the final formation of uric acid. Uric acid mainly by the urine excreted by the kidneys, a small part of excretion with the feces. In body fluids, uric acid combines with sodium ions to produce sodium urate, which, under normal conditions, has a saturation of 6.8 mg / dL. When the body produces excessive purine, more than the excretion of the kidneys, uric acid will accumulate in the blood and tissues. Hyperuricemia is called hyperuricemia when blood uric acid levels go beyond normal. Normally, blood uric acid concentration