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心源性猝死(SCD)和恶性室性快速性心律失常主要发生在早晨。现已证实,抗心律失常药物可以影响此种生理节奏的模式。β受体阻滞剂可降低SCD和室性快速性心律失常的晨间峰值,而氟卡尼(flecainide)、恩卡尼(encainide)和乙吗噻嗪(moricizine)
Sudden cardiac death (SCD) and malignant ventricular tachyarrhythmias occur mainly in the morning. It has been demonstrated that antiarrhythmic drugs can affect this pattern of circadian rhythms. Beta-blockers reduce the morning peak of SCD and ventricular tachyarrhythmia, while flecainide, encainide and moricizine