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妊娠期急性脂肪肝(AFLP)是妊娠期妇女特有的肝脏损害。其主要病变为妊娠期肝脏脂肪变性,常伴有肾、胰、脑等多脏器的损害。本院1973至1990年有5例妊娠期急性脂肪肝,同期分娩人数102701例,故发生率为1:20540次分娩;5例虽经积极抢救,仅1例产妇存活,4例死亡,孕产妇病死率为80％,双胎1例,死胎1例,新生儿死亡3例,新生儿存活2例,围产儿病死率为667‰。
Acute fatty liver during pregnancy (AFLP) is a unique liver damage in pregnant women. The main lesion of liver fatty degeneration during pregnancy, often accompanied by kidney, pancreas, brain and other organ damage. Our hospital from 1973 to 1990, 5 cases of acute fatty liver during pregnancy, the same period delivery number 102,701 cases, so the incidence rate of 1: 20540 deliveries; 5 cases despite active rescue, only 1 maternal death, 4 deaths, maternal The case fatality rate was 80%, one case of twins, one case of stillbirth, three cases of neonatal death, two cases of neonatal survival, and the perinatal mortality rate of 667 per thousand.