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选取新发宫颈癌患者100例及宫颈正常者100例作为研究对象,取其宫颈分泌物作标本,用多聚酶链反应(PCR)进行沙眼衣原体(Ct)检测,同时对所有研究对象进行有关因素的流行病学调查。结果发现,宫颈癌组Ct感染率为28%,明显高于对照组(6%)(P<0.01)。利用非条件Logistic回归模型进行单因素分析,筛选出14个有意义的因素。多因素分析结果显示,初婚年龄、痛经、初孕流产、爱人婚外性生活史、Ct感染及爱人文化程度等为与宫颈癌发生有关的主要危险因素
100 cases of newly diagnosed cervical cancer and 100 cases of normal cervix were selected as the research object. Cervical secretions were taken as samples and detected by polymerase chain reaction (PCR) for C. trachomatis (Ct). At the same time, all the subjects were studied Epidemiological Investigation. The results showed that cervical cancer Ct infection rate was 28%, significantly higher than the control group (6%) (P <0.01). Unconditional Logistic regression model for univariate analysis, screening out 14 significant factors. Multivariate analysis showed that age at first marriage, dysmenorrhea, first trimester abortion, lover extramarital life history, Ct infection and lover’s educational level are the main risk factors associated with cervical cancer