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目的观察44例老年糖尿病足(DF)患者血清脂类和载脂蛋白浓度值变化。方法连续选择44例近期近期就诊的老年DF患者,他们接受了血脂(总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白)和载脂蛋白(A和B)指标检测,并与41例同期就诊无DF的糖尿病患者(DM组)和39例同期体检结论健康者(对照组)比较。结果 DF组血清总胆固醇、甘油三酯、低密度脂蛋白和载脂蛋白B浓度均明显高于DM组和对照组,而高密度脂蛋白和载脂蛋白B则明显低于后两组(P均<0.05~0.01)。结论老年DF患者存在明确的血清脂类代谢紊乱。
Objective To observe the changes of serum lipids and apolipoproteins in 44 elderly patients with diabetic foot (DF). Methods Forty-four elderly patients with recent recent DF were enrolled in the study. They were tested for serum lipids (total cholesterol, triglyceride, low density lipoprotein, high density lipoprotein) and apolipoproteins (A and B) Cases of diabetic patients with no DF at the same period (DM group) and 39 cases of physical examination over the same period were compared (control group). Results The concentrations of serum total cholesterol, triglyceride, low density lipoprotein and apolipoprotein B in DF group were significantly higher than those in DM group and control group, while the levels of high density lipoprotein and apolipoprotein B in DF group were significantly lower than those in the latter two groups (P All <0.05 ~ 0.01). Conclusion There are definite disorders of serum lipid metabolism in elderly patients with DF.