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目的:研究抗白胶囊、祛白清髓汤、清髓祛瘤散治疗多发性骨髓瘤的治疗效果。方法:将68例多发性骨髓瘤患者随机分为治疗组32例和对照组36例,治疗组服用抗白胶囊、祛白清髓汤、清髓祛瘤散,对照组静脉注射卡莫司汀、环磷酰胺,并口服美法仑,比较两组患者的治疗效果。结果:治疗组32例中,治疗2个疗程后完全缓解13例,完全缓解率40.6%;部分缓解9例,部分缓解率28.1%;3个疗程后,完全缓解26例,完全缓解率81.3%。对照组36例中,治疗2个疗程后完全缓解7例,完全缓解率19.4%;部分缓解6例,部分缓解率16.7%;3个疗程后,完全缓解13例,完全缓解率36.1%。治疗组2个疗程和3个疗程的完全缓解率均高于对照组,差异均有统计学意义(P<0.05)。结论:抗白胶囊等三种复方制剂在多发性骨髓瘤不同阶段的疗程中具有良好的治疗效果,疗效优于卡莫司汀、环磷酰胺,值得临床推广应用。
Objective: To study the therapeutic effects of Kangai Bai Capsule, Qu Bai Decoction, and Qingdu Qumai San in the treatment of multiple myeloma. Methods: Sixty-eight patients with multiple myeloma were randomly divided into treatment group (n = 32) and control group (n = 36). The treatment group received anti-Bai capsule, Qu Bai Decoction, , Cyclophosphamide, and oral melphalan, compared the treatment effect of two groups of patients. Results: In the 32 cases of treatment group, 13 cases were completely relieved after 2 courses of treatment, the complete remission rate was 40.6%; the partial remission rate was 9% and the partial remission rate was 28.1%. After 3 courses of treatment, complete remission was achieved in 26 cases and the complete remission rate was 81.3% . In the control group of 36 cases, 7 cases were completely relieved after 2 courses of treatment and the complete remission rate was 19.4%; 6 cases were partially relieved and partial remission rate was 16.7%; 13 cases were completely relieved after 3 courses, and the complete remission rate was 36.1%. The complete remission rate of two courses and three courses of treatment group were higher than that of the control group, the difference was statistically significant (P <0.05). CONCLUSION: Three kinds of compound preparations such as anti-Bai capsule have good curative effect in different stages of multiple myeloma. The curative effect is better than that of carmustine and cyclophosphamide, which is worthy of clinical application.