Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C

• 作 者: Roba M. Talaat Ahmed A. Esmai
• 机 构: MolecularBiologyDepartments,RocheDiagnostics,DepartmentofTropicalMedicine
• 出 处: 癌症：英文版
• 发表日期: 2012年1期
• 关键词: 肿瘤坏死因子-α 单核苷酸多态性 丙型肝炎病毒 病毒感染 患者 肝癌 风险 聚合酶链反应 Tumor necrosis factor-a polymorphi

Tumor necrosis factor-alpha (TNF-α) is an important cytokine in generating an immune response against infection with hepatitis C virus (HCV). The functions of TNF-α may be altered by single-nucleotide polymorphisms (SNPs) in its gene structure. We hypothe