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目的观察体外高频热疗联合吉西他滨治疗晚期胰腺癌的临床效果。方法信阳市中心医院收治的晚期胰腺癌患者86例,随机分为研究组和对照组,每组各43例,对照组患者采用吉西他滨予以治疗,研究组患者采用体外高频热疗联合吉西他滨予以治疗,分析两组患者的疗效情况与不良反应发生率。结果研究组有效率为27.91%、疾病控制率69.77%均高于对照组有效率的16.28%与疾病控制率的46.51%,两组有统计学意义(P<0.05);研究组的不良反应发生率与对照组比较差异无统计学意义(P>0.05)。结论体外高频热疗联合吉西他滨治疗晚期胰腺癌患者有明显的疗效,能有效的改善患者生存质量。
Objective To observe the clinical effect of high frequency hyperthermia combined with gemcitabine in the treatment of advanced pancreatic cancer. Methods Totally 86 patients with advanced pancreatic cancer admitted to Xinyang Central Hospital were randomly divided into study group and control group, 43 cases in each group. The control group was treated with gemcitabine. The study group was treated with high frequency hyperthermia in combination with gemcitabine , Analysis of the efficacy of two groups of patients and the incidence of adverse reactions. Results The effective rate of the study group was 27.91%, the disease control rate was 69.77%, which was higher than that of the control group (16.28%) and disease control rate (46.51%), the two groups had statistical significance (P <0.05) There was no significant difference between the two groups (P> 0.05). Conclusion In vitro high-frequency hyperthermia combined with gemcitabine in patients with advanced pancreatic cancer has a significant effect, which can effectively improve the quality of life of patients.