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接枝共聚是一种在聚合物表面增强吸水性及阴极电荷以提高聚合物的生物相容性的有效方法。本文作者用辐射接枝甲基丙烯酸(MAA)与聚氯乙烯(PVC)薄膜,以异分子聚合,并用体外血栓产生,血小板粘附和溶血活性试验评价PVC表面的血栓形成状况。接枝共聚是在氮气环境中的标准接头管中进行。先将称量后的成形PVC薄膜放入均匀混合的甲醇-水溶液的安瓶中24小时。启开安瓶后立即加入MAA,放入辐射罩内进行辐射接枝。辐射后,除去PVC薄膜外层的同聚物溶液并用热水仔细
Graft copolymerization is an effective method to enhance the water absorption and the cathode charge on the polymer surface to improve the biocompatibility of the polymer. The authors evaluated the thrombus formation on PVC surfaces using radionuclide grafted MAA and polyvinyl chloride (PVC) films by heteropolymerization and in vitro thrombosis, platelet adhesion and hemolytic activity assays. Graft copolymerization is carried out in a standard adapter tube in a nitrogen atmosphere. The weighed shaped PVC film is first placed in a well-mixed methanol-water solution ampoule for 24 hours. Open the ampoule immediately after joining MAA, into the radiation shield for radiation grafting. After irradiation, remove the homopolymer solution from the outer layer of PVC film and carefully wash with hot water