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目的 :探讨1 31 I治疗后暂发性甲低的临床特点和转归。方法 :对 32例1 31 I治疗后出现暂发性甲低的患者进行临床分析和随访。结果 :暂发性甲低出现在1 31 I治疗后 2~ 6个月 ,有甲低症状者 19例 (5 9.38% )。甲低缓解后甲状腺功能正常者 2 0例 (6 2 .5 % ) ,又甲亢者 12例 (37.5 % )。甲低时 ,T3和T4 明显降低 ,TSH变化不一。结论 :暂发性甲低多发生在低剂量1 31 I治疗的患者 ,甲低缓解后部分患者可再次出现甲亢。
Objective: To investigate the clinical features and outcomes of temporary hypothyroidism after 131 I treatment. Methods: The clinical data and follow-up of 32 patients with temporary hypothyroidism after 131 I treatment were analyzed. Results: Transient hypothyroidism occurred in 1 ~ 6 months after 131 I treatment, 19 cases (5 9.38%) had hypothyroidism. A hypothyroidism after thyroid function were normal 20 cases (62.5%), and hyperthyroidism in 12 cases (37.5%). A low, T3 and T4 decreased significantly, TSH changes. Conclusions: Temporary hypothyroidism occurs mostly in patients treated with low-dose 1 31 I, and hyperthyroidism may recur in some patients after hypothyroidism.