论文部分内容阅读
目的:探讨血管危险因素与颅内动脉狭窄的严重程度和狭窄部位的相关性。方法:以64排CTA作为检测手段,142例患者纳入研究,将狭窄率在中度、重度及闭塞的患者作为观察组,而血管正常及轻度狭窄(≤29%)的患者作为对照组。将16个因素在观察组和对照组之间行对比分析,并对危险因素与狭窄部位的关系进行研究。结果:单因素分析显示,观察组高血压史(P=0.00)、糖尿病史(P=0.008)、脑卒中史(P=0.008)的构成比明显高于对照组。Logistic回归分析显示,脑梗塞史、高血压史是颅内动脉狭窄的独立危险因素。对危险因素与狭窄部位的关系进行了分析,结果显示有血脂异常史的患者更易在前后循环同时出现狭窄;而高血压病史、糖尿病史、脑梗死史、长期吸烟史、长期饮酒史与狭窄部位并无明显相关性。结论:脑梗塞史、高血压史是颅内动脉狭窄的独立危险因素,有血脂异常史的患者更易在前后循环同时出现狭窄。
Objective: To investigate the relationship between vascular risk factors and the severity of intracranial arterial stenosis and stenosis. Methods: Totally 64 patients with CTA were included in the study. 142 patients were included in the study. Patients with moderate, severe and occlusive disease were included in the study. Patients with normal and mild stenosis (≤ 29%) were selected as control group. Sixteen factors were compared between the observation group and the control group, and the relationship between the risk factors and the stenosis was studied. Results: Univariate analysis showed that the constituent ratio of hypertension in observation group (P = 0.00), history of diabetes (P = 0.008) and history of stroke (P = 0.008) was significantly higher than that in control group. Logistic regression analysis showed that the history of cerebral infarction and hypertension were independent risk factors of intracranial artery stenosis. The relationship between the risk factors and the location of the stenosis was analyzed. The results showed that patients with a history of dyslipidemia were more likely to have stenosis in both anterior and posterior circulation. Hypertension, diabetes mellitus, history of cerebral infarction, long-term smoking, long-term alcohol consumption and stenosis There is no obvious correlation. Conclusion: The history of cerebral infarction and hypertension are independent risk factors of intracranial arterial stenosis. Patients with history of dyslipidemia are more likely to have stenosis in both anterior and posterior circulation.