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到目前为止,预防输血反应的药物仍不理想。甲氰咪胍是一种免疫调节剂业且在上消化道出血中广泛地应用着,因此我们设想把此药作为预防输血反应,现将一些情况介绍如下以供讨论。资料和方法:均为住院病人,共309例次,男201例次,女108例次。其中使用甲氰咪胍184例次,非那根67例次,可拉明58例次。以上消化道出血最多占68.4％,病因有胃、十二指肠球部溃疡,胃炎,食道静脉破裂出血,胃癌等。治疗方法:1.甲氰咪胍组使用每100毫升血中加甲氰咪胍100毫克,2.非那根组使用输血前肌注非那根25毫克,3.可拉明组使用每100毫升血中加可拉明0.375克。
So far, drugs to prevent transfusion reactions are still not ideal. Cimetidine is an immunomodulator and is widely used in upper gastrointestinal bleeding. Therefore, we envisaged the use of this drug as a prophylaxis of transfusion reactions. We will present some of the information below for discussion. Materials and Methods: All inpatients were 309, with 201 males and 108 females. Among them, there were 184 cases of cimetidine, 67 cases of phenanthrene and 58 cases of Clyamine. More than the upper gastrointestinal bleeding accounted for 68.4%, the cause of stomach, duodenal ulcer, gastritis, esophageal variceal bleeding, stomach cancer. Treatment: 1. Cimetidine group used per 100 ml of blood plus cimetidine 100 mg, 2. Fane group used before transfusion of intramuscular injection of phenacepin 25 mg, 3. Cloram group used every 100 Ml blood plus civet 0.375 grams.