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儿茶酚胺类(CAs)化合物是人体内重要的生理活性物质,主要包括肾上腺素(E)、去甲肾上腺素(NE)及多巴胺(DA)。尿中CAs的水平不仅可作为嗜铬细胞瘤等疾病的诊断标准,而且与肾功能关系密切,因此具有重要的临床诊断和研究价值。 CAs在体液中含量低,以往用萤光分光光度法只能测E和NE的总量,无法测DA。采用HPLC-UV法虽能分别测定上述三种物
Catecholamines (CAs) are important physiologically active substances in the human body and mainly include epinephrine (E), norepinephrine (NE) and dopamine (DA). The level of urine CAs not only as a diagnostic criteria for diseases such as pheochromocytoma, but also closely related to renal function, it has important clinical diagnosis and research value. CAs in the body fluid content is low, in the past using fluorescent spectrophotometry can only measure the total amount of E and NE, can not be measured DA. Although HPLC-UV method can be used to determine the above three substances respectively