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脂质过氧化物体增殖物激活受体(PPARs)是一组配体激活的核转录因子,在体内组织广泛表达并具有多种生物学效应;其中PPARγ激动剂可能直接或间接作用于肾脏而发挥其肾脏保护作用。该文就PPARγ与糖尿病肾病关系的研究进展作一综述。
Lipid peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear transcription factors that are widely expressed in tissues and have multiple biological effects; PPARγ agonists may act directly or indirectly on the kidneys Its renal protective effect. This article reviewed the research progress of the relationship between PPARγ and diabetic nephropathy.