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目的：分析氯吡格雷联合低分子肝素钠治疗老年不稳定型心绞痛的疗效。方法选择深圳市宝安区石岩人民医院2012年5月至2014年5月收治的70例不稳定型心绞痛老年患者为研究对象，随机将其分为两组，对照组给予常规治疗，观察组在对照组基础上行氯吡格雷联合低分子肝素钠治疗，比较两组患者的临床疗效、不良反应、治疗前后心绞痛发作次数、总胆固醇（TC）水平及随访1个月心血管事件发生情况。结果观察组治疗总有效率、随访1个月时心绞痛再发及心肌梗死发生率分别为94.3%、2.8%、0，与对照组的74.3%、17.1%、11.4%比较差异有统计学意义（ P ＜0.05）。观察组治疗后心绞痛发作次数、TC 水平明显低于对照组（P ＜0.05）。两组不良反应发生率比较差异未见统计学意义（P ＞0.05）。结论氯吡格雷联合低分子肝素钠治疗老年不稳定型心绞痛疗效明确，能有效预防心肌梗死等不良心血管事件发生。“,”Objective To analyze the curative effect of clopidogrel combined with low molecular heparin sodium in treatment of elderly patients with unstable angina pectoris. Methods Seventy elderly patients with of unstable angina pectaris from May 2012 to May 2014 were selected as the research object and were randomly divided into two groups,the control group was given routine treatment,and patients in the observation group was given clopidogrel combined with low molecular weight heparin sodium treatment on the basis of control group,the clinical curative effect,adverse reactions,angina attack frequency before and after the occurrence,level of TC and cardiovascular events followed up for 1 months of two groups were compared. Results The total efficiency of treatment,angina recurrence after 1 months and the incidence of myocardial infarction in observation group were 94. 3% ,2. 8% ,0,compared with control group of 74. 3% ,17. 1% ,11. 4% ,the differences were statistical significance(P <0. 05). The frequency of angina pectoris,TC levels in observation group after treatment were significantly lower than those of control group(P 0. 05). Conclusion The effect of clopidogrel combined with low molecular heparin sodium in treatment of senile unstable angina pectoris is clear,can prevent myocardial infarction and other adverse cardiovascular events.