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目的观察硫酸镁和酚妥拉明治疗毛细支气管炎的疗效。方法将2010年3月-2012年3月收治的120例毛细支气管炎患儿随机分为治疗组60例,对照组60例,两组均常规给予镇静、吸氧、雾化、抗感染、止咳祛痰平喘等治疗,治疗组除给予常规治疗外,同时给予硫酸镁联合酚妥拉明微泵输液治疗,一般用3~5 d为一个疗程,对照组仅给予常规治疗。结果治疗组治愈52例,好转7例,无效1例,总有效率98.4%;对照组治愈41例,好转12例,无效7例,总有效率88.3%。治疗组总有效率明显高于对照组,两组比较差异有统计学意义(P<0.05)。结论应用硫酸镁联合酚妥拉明治疗毛细支气管炎临床疗效显著,是一种安全有效的方法,值得临床推广。
Objective To observe the curative effect of magnesium sulfate and phentolamine on bronchiolitis. Methods A total of 120 children with bronchiolitis admitted from March 2010 to March 2012 were randomly divided into treatment group (60 cases) and control group (60 cases). Both groups were given routine sedation, oxygen inhalation, atomization, anti-infection and cough suppression Expectorant and antiasthmatic treatment, the treatment group in addition to giving conventional treatment, while given magnesium sulfate phentolamine micro pump infusion therapy, usually with 3 ~ 5 d for a course of treatment, the control group was given only conventional treatment. Results In the treatment group, 52 cases were cured, 7 cases improved, 1 case ineffective and the total effective rate was 98.4%. In the control group, 41 cases were cured, 12 cases improved, 7 cases were ineffective, and the total effective rate was 88.3%. The total effective rate of the treatment group was significantly higher than that of the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion The application of magnesium sulfate combined with phentolamine treatment of bronchiolitis significant clinical effect, is a safe and effective method, worthy of clinical promotion.