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目的:研究重症胰腺炎患者食管内镜下和动力学表现及生长抑素和生长激素联合应用对其的影响。方法:对44例重症胰腺炎患者随机分为单用生长抑素组(20例)、生长抑素和生长激素联合应用组(24例),以内镜检查和液体灌注式食管测压法评价食管炎症和动力学变化。结果:重症胰腺炎患者并发食管糜烂和动力学异常。与生长抑素单用比较,联合应用使食管糜烂愈合、食管远端蠕动波幅和蠕动速度改善更明显(P<0.05)。结论:生长抑素和生长激素联合应用使重症胰腺炎患者食管炎症和动力学改善。
Objective: To study the esophagoscopy and kinetics of severe pancreatitis and the effect of combination of somatostatin and somatostatin on it. Methods: Forty-four patients with severe acute pancreatitis were randomly divided into single use of somatostatin (n = 20), somatostatin and growth hormone (n = 24). The endoscopic and liquid perfusion esophageal manometry Inflammation and kinetic changes. Results: Patients with severe pancreatitis complicated by esophageal erosion and kinetic abnormalities. Compared with somatostatin alone, the combined application of esophageal erosion and esophageal healing, esophageal distal peristalsis amplitude and peristaltic speed to improve more significantly (P <0.05). Conclusion: The combination of somatostatin and growth hormone can improve esophageal inflammation and kinetics in patients with severe acute pancreatitis.