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设计了用于游离细胞生物转化的反冲式膜反应器，反应器内增加搅拌装置以减轻细胞对膜的堵塞。实验体系采用含天冬氨酸酶的大肠杆菌细胞转化反丁烯二酸为Ｌ－天冬氨酸。研究了膜孔径大小和细胞浓度对反应器的影响。并与利用固定细胞的填充床反应器进行了比较
A recoil-type membrane reactor for free-cell biotransformation was designed and a stirrer was added to the reactor to reduce the cell clogging of the membrane. Experimental system Aspartase-containing E. coli cells were used to convert fumaric acid to L-aspartic acid. The effects of membrane pore size and cell concentration on the reactor were investigated. And compared to packed bed reactors using fixed cells