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目的:从病理学角度分析120例幽门螺杆菌阳性慢性浅表性胃炎(chronic superficial gastritis,CSG)的组织学特征。方法:用电子胃镜对确诊的120例幽门螺杆菌阳性CSG患者的炎症活动性、慢性炎症、血管病变、上皮损伤、腺体萎缩、不典型增生及肠化生等组织形态学指标进行回顾性分析。结果:CSG病人的黏膜具有急性炎症、慢性炎症、血管病变、上皮损伤,分别高达97．5％(117／ 120)、98．3％(118／120)、95．8％(115／120)、70％(84／120),腺体萎缩、不典型增生及肠化生的发生率约为35％-39．2％,组织学改变均以1级占多数。结论:急、慢性炎症细胞浸润,血管病变及上皮损伤是幽门螺杆菌阳性CSG的组织学基础,其慢性黏膜病变的组织学改变均以1级为主。
Objective: To analyze the histological features of 120 chronic Helicobacter pylori-positive chronic superficial gastritis (CSG) from the perspective of pathology. Methods: The histopathological features of inflammatory, chronic inflammation, vascular lesions, epithelial lesions, glandular atrophy, atypical hyperplasia and intestinal metaplasia of 120 confirmed H. pylori-positive CSG patients were retrospectively analyzed by electronic endoscopy . Results: The mucosa of CSG patients had acute inflammation, chronic inflammation, vascular lesions and epithelial injury, reaching 97.5% (117/120), 98.3% (118/120) and 95.8% (115/120) respectively. , 70% (84/120). The incidence of glandular atrophy, dysplasia and intestinal metaplasia was about 35% -39.2%. The histological changes were mostly in the first grade. Conclusion: The acute and chronic inflammatory cell infiltration, vascular lesions and epithelial injury are the histological basis of Helicobacter pylori-positive CSG. The histological changes of chronic mucosal lesions are mainly grade 1.