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本文研究了２５倒尿毒症患者血清胃泌素对胃粘膜病变的影响，结果胃粘膜病理报告均为胃窦炎，尿毒症患者血清同泌素显著高于对照组（Ｐ＜０．０１），有胃粘膜糜烂出血者血清胃泌素水平高于无胃粘膜糜烂出血者（Ｐ＜０．０５），重度胃炎者血清胃泌素高于轻度胃炎者（Ｐ＜０．０５）．提示血清高胃泌素血症可能是尿毒症胃粘膜病变的原因。
In this study, we investigated the effects of serum gastrin on the pathological changes of gastric mucosa in 25 patients with uremia. Results The pathological reports of gastric mucosa were antral gastritis. Serum endocrine levels were significantly higher in patients with uremia (P <0.01) The level of serum gastrin in patients with gastric mucosal erosions was higher than those without gastric mucosal erosions (P <0.05). Serum gastrin was higher in patients with severe gastritis than those with mild gastritis (P <0.05). Prompt serum gastrin hyperlipidemia may be the cause of uremic gastric mucosal lesions.