论文部分内容阅读
本文报道了在7个国家的10个研究中心分别对21～45岁的健康男性每周肌肉注射200mg庚酸睾丸酮,导致无精子症而进行男性避孕,最大规模地评估外源性睾酮对正常男性代谢及其它生理功能的影响,并比较了其它性激素男性避孕的副作用。研究对象为271人(31.8±5.4岁),其中中国人组82例(35.2±4.5岁),非华人组189例(30.3±5.1岁)。 结果:用药6月内有157例(58％)发生无精子症,另外68例(25％)未发生无精子症。46
In this paper, we report that intramuscular injection of 200 mg of testosterone enanthate to healthy men aged 21-45 years at 10 research centers in seven countries led to azoospermia for male contraception and the largest assessment of the effect of exogenous testosterone on normal male Metabolism and other physiological functions, and compared the contraceptive side effects of other sex hormones. The study population was 271 (31.8 ± 5.4 years), of whom 82 (35.2 ± 4.5) years in Chinese and 189 (30.3 ± 5.1 years) in non-Chinese subjects. Results: There were 157 cases (58%) with azoospermia in June and 68 cases (25%) without azoospermia. 46