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本文对幽门螺杆菌阴性(Hp-)和阳性(Hp+)慢性胃炎病例的胃酸分泌量进行了比较研究。结果发现 Hp(+)组比 Hp(-)组有高的高峰胃酸分泌量(P<0.001),提示 Hp对胃酸分泌调控具有干扰作用。Hp 的寄生除造成胃、十二指肠粘膜的损伤外,还使胃酸分泌增多,二者相结合可能是 Hp 致病的机制之一。
In this paper, H. pylori-negative (Hp-) and positive (Hp +) chronic gastritis cases of gastric acid secretion were compared. The results showed that the Hp (+) group had higher peak gastric acid secretion than the Hp (-) group (P <0.001), suggesting that Hp may interfere with the regulation of gastric acid secretion. Hp parasites in addition to causing stomach, duodenal mucosal injury, but also increased gastric acid secretion, the combination of the two may be one of the mechanisms of Hp pathogenesis.