不同孕期妇女胎盘组织中P物质含量的变化

• 作 者: 焦金菊 周丰 常志杰 庄晓燕 姜思魁 李锦
• 出 处: 锦州医学院学报
• 发表日期: 2000年03期
• 关键词: 胎盘组织 孕期妇女 P物质 晚期妇女 妊娠 湿重 放射免疫测定 妊娠生理 中期 妊娠天数

为探讨 P物质 (substance P,SP)对妊娠生理过程的影响 ,本文应用放射免疫分析方法 ,测定了妊娠中、晚期妇女胎盘组织中 SP的含量。结果显示 :妊娠中、晚期妇女胎盘组织中均含有 SP。中期 SP的含量为 (2 3 .4 2±2 .53 ) pg/ mg湿重组织 ,晚期为 (9.91± 0 .96) pg/ mg。两组 SP的含量差异显著 (P<0 .0 1 )。此结果提示 SP可能在妊娠这一复杂的生理过程中起某种调控作用。

In order to investigate the effect of substance P (SP) on the physiological process of pregnancy, the content of SP in the placenta of middle and late pregnancy women was determined by radioimmunoassay. The results show that: pregnancy, late women have placental tissue SP. The content of mid-term SP was (23.32 ± 2.53) pg / mg wet weight tissue, and the late phase was (9.91 ± 0.96) pg / mg. The content of SP in the two groups differed significantly (P <0.01). This result suggests that SP may play a regulatory role in the complex physiological process of pregnancy.