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为探讨哮喘患者中医辨证分型与肾功能的关系,我们用放免法测定217例哮喘患者UAlb、UIgG、Uβ_2-m、UTHP(统称为4UP)含量,并选择其中30例同时测定血清BUN、Cr含量,分别与4UP逐项进行相关分析,结果报道如下。 对象和方法 一、对象:217例哮喘患者按中华医学会呼吸系病学会1993年标准确定诊断。均排除肾功能异常性疾病。男性107例,女性110例,平均年龄43.5±16.4(10～74)岁。按文献报道的方法分型,属于外源性哮喘157例,内源性哮喘60例;发作期138例,缓解期79例;病情程度轻度82例,中度115例,重度20例。另66例部队体检健康者作为正常对照组。 中医辨证分型按文献报道方法分为三型,属肺虚型96例,肺脾两虚型44例,肺肾两虚型77例。 二、方法:全部受检者于上午8:00～9:00留取中段尿,10～20ml并抽静脉血3ml分离血清保存。4UP
To investigate the relationship between TCM syndrome differentiation and renal function in asthmatic patients, the levels of UAlb, UIgG, Uβ_2-m and UTHP (collectively referred to as 4UP) in 217 asthmatic patients were determined by radioimmunoassay and 30 of them were selected for simultaneous determination of serum BUN, Cr Content, respectively, and 4UP related analysis of one by one, the results reported below. Subjects and methods First, the object: 217 cases of asthma patients by the Chinese Medical Association Respiratory Society 1993 standards to determine the diagnosis. Are excluded renal dysfunction disease. 107 males and 110 females, with an average age of 43.5 ± 16.4 (10 ~ 74) years old. According to the methods reported in the literature, 157 cases were extrinsic asthma, 60 cases were endogenous asthma, 138 cases were exacerbation and 79 cases were remission. The severity of illness was 82, moderate and 20 cases. Another 66 cases of physical examination as a normal control group. TCM syndromes were divided into three types reported in the literature, which is 96 cases of lung deficiency, lung and spleen deficiency in 44 cases, lung and kidney deficiency in 77 cases. Second, methods: All subjects were taken in the morning 8: 00 ~ 9: 00 urine, 10 ~ 20ml and venous blood 3ml serum was separated. 4UP