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于1979年1～4月及1980年2～5月搜集10岁以上急性中耳炎病人78例,分为两组:一组用苯氧甲基青霉素治疗,剂量为0.8克,2次/日,10天为一疗程;另一组用红霉素治疗,剂量为0.5克,2次/日,10天为一疗程。为观察治疗效果,于病人初诊时、治疗期间及治疗后期分别取其鼻咽部拭子进行致病菌的分离鉴定,测定病人初诊时及恢复期血清中肺炎双球菌自溶酶(pneumolysin)抗体、流感嗜血杆菌的补体结合抗体,效价增大四倍作为阳性。并测定初诊病人的C-反应蛋白含量。结果发现:78例初诊病人分离流感嗜血杆菌阳性者为28例,肺炎链球菌(即肺炎双球菌——译者)阳性者26例;应用抗生素治疗7～9天时复查细菌培养结果,47例病人中流感
From January to April 1979 and from February to May 1980, 78 patients with acute otitis media over 10 years old were enrolled and divided into two groups: one group treated with phenoxymethylpenicillin at a dosage of 0.8 g twice daily, Days for a course of treatment; the other group with erythromycin treatment, a dose of 0.5 grams, 2 times / day, 10 days for a course of treatment. In order to observe the therapeutic effect, nasopharyngeal swabs were isolated and identified during the initial diagnosis, treatment and post-treatment, respectively. The levels of pneumolysin antibodies , The complement of H. influenzae binds to the antibody and the titer increases fourfold as positive. And determine the newly diagnosed patients with C-reactive protein content. The results showed that: Among the 78 newly diagnosed cases, 28 cases were positive for Haemophilus influenzae, 26 cases were positive for Streptococcus pneumoniae (Pneumococci - Translator), 47 cases were examined for bacterial culture with antibiotics for 7 to 9 days, Flu in the patient