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近年来随着乙肝疫苗的研制成功,在高发的易感儿童中日渐广泛地进行着乙肝疫苗的接种。但是经免疫后机体的应答情况、效果的评价尚存在一些问题。为了解决这些问题,我们于1989年5～7月份,对曾接种乙肝疫苗的247名儿童进行了免疫后抗—HBs水平的调查,现将结果报告如下: 材料与方法一、乙型肝炎血源疫苗:是卫生部北京生物制品研究所生产,疫苗含量为10ug/ml。二、调查对象:选择近三年内曾完成乙肝疫苗免疫的12岁以下儿童,在免疫前均经RPHA法检测HBsAg为阴性的列为调查对象。
In recent years, with the successful development of hepatitis B vaccine, in the high incidence of susceptible children more and more hepatitis B vaccination. However, after the immune response to the body situation, the evaluation of the effects of some problems. In order to solve these problems, we investigated the anti-HBs levels of 247 children who had been vaccinated against hepatitis B from May to July 1989. The results are reported as follows: Materials and Methods 1. Hepatitis B blood Vaccine: Beijing Institute of Biological Products Ministry of Health production, the vaccine content of 10ug / ml. Second, the survey: Select the past three years have completed the hepatitis B vaccine immunization of children under the age of 12, were detected by RPHA before immunization as a negative HBsAg as a survey.