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目的 观察早期高压氧治疗新生儿缺血缺氧性脑病的临床疗效.方法 将42例缺血缺氧性脑病患儿随机分为治疗组21例和对照组21例,对照组只给予综合治疗,治疗组在综合治疗的基础上加用高压氧治疗,然后观察临床症状的变化情况.结果 治疗组总有效率86.4%,显著高于对照组的63.6%(P<0.05).结论 早期高压氧对治疗新生儿缺血缺氧性脑病有显著疗效.“,”Objective To observe the effect of hyperbaric oxygen therapy on neonatal hypoxicischemic encephalopathy(HIE). Methods Forty-two cases of HIE were randomly divided into treatment group and control group, the control group just give comprehensive treatment, the treatment group in comprehensive therapy combined with hyperbaric oxygen therapy, then observe the changes of clinical symptoms. Results The treatment group total efficient rate (86.4%) was higher than that in control group (63.6%),P<0.05.Conclusion Hyperbaric oxygen therapy on neonatal hypoxicischemic encephalopathy has remarkable curative effect.