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应用浓缩尿平板测定法对495例各种病人及健康人的尿液溶菌酶作了测定,认为方法简单易行、重复性能好,对肾脏疾病特别是肾小管损害具有一定诊断价值。健康人尿溶菌酶大多在1.0微克/毫升以下,如超过2.0微克/毫升可能存在肾小管损害。尚可用于诊断肾小管-间质性疾病;区别功能性肾衰竭及肾小管坏死;判断急性肾功能衰竭的病情变化;了解肾小球疾患是否合并间质性损害,有助于判断预后。
Urine lysozyme was determined in 495 cases of various patients and healthy people by using concentrated urine test. The method is simple, reproducible and has certain diagnostic value for renal diseases, especially renal tubular damage. Most human urine lysozyme at 1.0 micrograms / ml below, such as more than 2.0 micrograms / ml possible tubular damage. Can be used to diagnose tubulointerstitial disease; distinguish between functional renal failure and tubular necrosis; to determine the severity of acute renal failure; to understand glomerular disease with interstitial damage, help to determine the prognosis.