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目的对可能导致口腔扁平苔藓(OLP)发病的相关风险因素进行调查分析,为防治扁平苔藓提供理论依据。方法选取符合条件的口腔扁平苔藓患者130例,与近期在我院健康体检的130例非口腔黏膜病患者进行对照研究,将相关调查数据行二分类多因素Logistic回归分析,以筛查OLP发病的相关风险因素。结果经Logistic回归分析结果显示,心理因素、胃炎、局部理化刺激和自主神经紊乱与OLP发病具有显著相关性。结论口腔扁平苔藓发病及病情进展与多因素有关,临床应有效进行病因治疗以促进OLP的预防及预后。
Objective To investigate the risk factors that may lead to the development of oral lichen planus (OLP) and provide a theoretical basis for the prevention and treatment of lichen planus. Methods A total of 130 patients with oral lichen planus who met the criteria were selected and compared with 130 non-oral mucosal disease patients who were recently examined in our hospital. Logistic regression analysis was used to investigate the prevalence of OLP Related risk factors. Results Logistic regression analysis showed that psychological factors, gastritis, local physical and chemical stimuli and autonomic disorders were significantly associated with the incidence of OLP. Conclusion The incidence and progression of oral lichen planus are related to many factors, and clinical treatment should be effective to promote the prevention and prognosis of OLP.