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本文测定了微量元素硒缺乏大鼠眼晶体某些酶活性、自由基以及过氧化物含量,结果表明缺硒使大鼠晶体谷胱甘肽过氧化物酶活性显著下降,晶体谷胱甘肽过氧化物酶活性与红细胞硒水平呈显著的正相关。缺硒使晶体丙二醛含量显著升高。缺硒组及对照组大鼠晶体中均有g=2.0015的自由基存在,但缺硒组自由基含量显著高于对照组,晶体自由基含量与红细胞硒水平以及晶体谷胱甘肽过氧化物酶活性呈显著的负相关。短暂的短波紫外线照射离体晶体,诱发晶体产生g=2.0097的自由基,缺硒组自由基的增加量也显著地高于对照组。因此硒缺乏导致大鼠晶体抗氧化能力下降,脂质过氧化作用加强,自由基产生增加。
In this paper, the determination of trace element selenium deficiency in some eye crystals of rats activity, free radicals and peroxide content, the results show that the lack of selenium in rats with a significant reduction in glutathione peroxidase activity, glutathione Oxidase activity and red blood cell selenium levels showed a significant positive correlation. Selenium deficiency significantly increased the content of crystalline malondialdehyde. There were free radicals with g = 2.0015 in the selenium-deficient group and the control group, but the content of free radicals in the selenium-deficient group was significantly higher than that in the control group. The contents of free radical and erythrocyte selenium and crystal glutathione peroxides Enzyme activity showed a significant negative correlation. Short-wave ultraviolet irradiation of isolated crystals, crystal induced g = 2.0097 free radicals, the lack of selenium group free radicals increased significantly higher than the control group. Therefore, the lack of selenium lead to decreased anti-oxidative capacity of rat crystals, lipid peroxidation and enhanced free radical production.