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目的:观察盐酸丁咯地尔治疗椎一基底动脉供血不足的疗效及不良反应。方法:104例患者随机分为治疗组和对照组,治疗组52例,丁咯地尔200mg静脉滴注,1次/天,疗程7天,对照组52例,川芎嗪120mg静脉滴注,1次/天,疗程7天,观察两组患者疗效及不良反应。结果:治疗组显效率及总有效率分别为65.4%和90.4%,均明显高于对照组25%和67.3%,差异有显著性(P<0.01和P<0.05),两组均无明显不良反应。结论:盐酸丁咯地尔治疗椎一基底动脉供血不足疗效显著,无明显不良反应。
Objective: To observe the efficacy and adverse reactions of buflomedil hydrochloride in the treatment of vertebrobasilar insufficiency. Methods: One hundred and forty-four patients were randomly divided into treatment group and control group. The treatment group was treated with intravenous infusion of buflomedil 200mg once a day for 7 days. The control group received intravenous infusion of 120mg tetramethylpyrazine Times / day, the course of treatment for 7 days to observe the efficacy and adverse reactions of two groups of patients. Results: The effective rate and total effective rate in the treatment group were 65.4% and 90.4%, respectively, which were significantly higher than those in the control group (25% vs 67.3%, P <0.01 and P <0.05) reaction. CONCLUSION: Buflomedil hydrochloride is effective in treating vertebrobasilar artery insufficiency with no obvious side effects.