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太原市清徐县吴村常年饮水中锰含量过高，小学生发锰、血锰含量分别为１．２４２ｕｇ／ｇ、６１７ｎｍｏｌ／Ｌ（３．３９ｕｇ／ｄｌ）。均高于正常儿童，学习成绩则低于正常儿童。为了探讨体内锰含量过高与学习能力低下的关系，作者测定了该村９２名小学生的血清５－羟色胺、多巴胺、去甲肾上腺素和乙酰胆碱酯酶，结果４种神经递质均低于正常儿童。学习成绩（语文、数学、总平均分）与多数神经递质呈正相关。多元线性回归结果表明：影响语文和总平均分成绩的神经递质顺序为５－羟色胺、去甲肾上腺素、乙酰胆碱酯酶和多巴胺，影响数学成绩的神经递质顺序为去甲肾上腺素、５－羟色胺、乙酰胆碱酯酶和多巴胺。
Taiyuan Qingxu County, Wu Village, perennial drinking water is too high manganese content, primary students hair manganese, blood manganese levels were 1.242ug / g, 617nmol / L (3.39ug / dl). Higher than normal children, academic performance is lower than normal children. In order to explore the relationship between the excessive manganese content and low learning ability in the body, the authors measured serum serotonin, dopamine, norepinephrine and acetylcholinesterase in 92 primary school students. The results showed that the four neurotransmitters were lower than normal children . Academic achievement (language, math, overall average) was positively correlated with most neurotransmitters. The results of multiple linear regression showed that the order of neurotransmitters that affect language and overall average score was serotonin, norepinephrine, acetylcholinesterase and dopamine. The order of neurotransmitters that affect math scores was norepinephrine, 5- Serotonin, acetylcholinesterase and dopamine.