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永久性肝动脉结扎（ＰＨＡＬ）后侧枝循环的建立．是ＰＨＡＬ治疗肝癌效果不持久的原因之一．如何防止或减少侧枝循环的形成．是肝癌缺血治疗的重要环节之一。通过大鼠选择性腹腔动脉造影（ＳＣＡ）的方法．观察ＰＨＡＬ和肝动脉反复暂时阻断（ＲＴＢＨＡ）后侧枝形成的情况。ＰＨＡＬ后２ｗｋＳＣＡ即可见侧枝循环．随着时间延长．侧枝愈加明显丰富，其主要来源是肠系膜上动脉、腹腔动脉和大网膜。ＲＴＢＨＡ后２ｗｋ，ＳＣＡ未显示侧枝形成。实验结果表明肝动脉的间歇阻断可以防止侧枝循环的建立。这为ＲＴＢＨＡ的临床运用提供了实验依据。
Establishment of collateral circulation after permanent hepatic artery ligation (PHAL). PHAL treatment of liver cancer is not one of the reasons long-lasting effect. How to prevent or reduce the formation of collateral circulation. Is an important part of the treatment of liver cancer ischemia. Selective celiac artery angiography (SCA) method in rats. To observe the PHAL and hepatic artery after repeated temporary block (RTBHA) after the formation of collateral conditions. 2wkSCA can be seen after PHAL collateral circulation. As time goes by. Side branches are significantly more abundant, the main source is the superior mesenteric artery, celiac artery and omentum. 2 weeks after RTBHA, SCA did not show collateral formation. Experimental results show that intermittent hepatic artery blockage can prevent the establishment of collateral circulation. This provides an experimental basis for the clinical use of RTBHA.