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67例53～82岁2型糖尿病病人(男48例,女19例)按年龄、病程各分为3组,根据OGTT参数计算新β细胞功能指数MBCI,MBCI=(FINS×FPG)/(PG2h+PG1h-2×FPG)(FINS:空服胰岛素,FPG:空服血糖,PG1h和PG2h分别为OGTT1h和2h血糖)探讨在临床工作中以OGTT的简单参数评估β细胞功能的可能性。结果:按年龄分为3组,MBCI值在70岁以下与年龄关系不大,而70岁以上与年龄关系明显,在病程中无明显差异,在临床工作中可用与评价糖尿病患者的β细胞功能,以指导治疗。
Sixty-seven patients with type 2 diabetes mellitus (48 males and 19 females) aged 53-82 years were divided into 3 groups according to their age and duration. MBCI, MBCI = (FINS × FPG) / (PG2h) were calculated according to OGTT parameters + PG1h-2 × FPG) (FINS: Insulin, FPG: blood glucose, PG1h and PG2h respectively OGTT1h and 2h blood glucose) To investigate the possibility of assessing β-cell function with simple parameters of OGTT in clinical practice. Results: The patients were divided into three groups according to their age. The MBCI values were not related to the age under 70 years old, while the age over 70 years old was obviously related to the age. There was no significant difference in the course of the disease. The β-cell function of diabetic patients could be used and evaluated , To guide the treatment.