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30例轻度铅中毒PSP排泄试验、血尿酸、β_2MS、β_2MU及临床检查结果显示:①中毒组异常者与正常组有显著差异(P<0.01)。②血铅、尿铅与β_2MU增高相关。③铅中毒组驱铅后β_2MU水平降低。上述结果说明,可能有近曲小管的潜在性、可逆性亚临床慢性肾损害,β_2MU作为肾损害的筛选指标,有助于早期诊断。
30 cases of mild lead poisoning PSP excretion test, serum uric acid, β_2MS, β_2MU and clinical examination results showed: ① poisoning group was significantly different from the normal group (P <0.01). ② blood lead, urine lead and β_2MU increased correlation. ③ lead poisoning group lead_2MU level after lead reduction. The above results suggest that there may be proximal tubule potential, reversible subclinical chronic kidney injury, β 2 MU as a screening indicator of renal damage, contribute to the early diagnosis.