论文部分内容阅读
目的:回顾性分析休克、感染、年龄、主要致伤部位等因素对多发伤病员发生多器官功能障碍综合征(MODS)的影响。方法:对 MODS 与非 MODS 病员及各影响因素分组,进行双向分析比较。共122例多发伤伤员进入该项研究。结果:全组损伤严重程度评分(ISS)21.2±8.64,32例发生 MODS,MODS 组与非 MODS 组在年龄、性别和 ISS 等方面均无明显差异,但病死率(56%vs.3.3%,P<0.01)和合并感染率(87.5%vs.62.8%,P<0.05)差异显著。另外,在休克与非休克组,感染与非感染组,MODS 的发生率差异显著(分别为31.9%vs.18%,P<0.05;38.9%vs.8%,P<0.001)。主要受伤部位对 MODS 发生的影响亦不显著。结论:感染依然与严重多发伤后发生 MODS 关系最密切。与之相比,休克在诱发 MODS 上的重要性已经下降。
OBJECTIVE: To retrospectively analyze the effects of shock, infection, age, major injury sites and other factors on multiple organ dysfunction syndrome (MODS) in multiple injuries. Methods: The patients with MODS and non-MODS and the influencing factors were divided into two groups for bidirectional analysis and comparison. A total of 122 cases of multiple injuries into the study. Results: There was no significant difference in the age, sex and ISS between the MODS group and the non-MODS group (21.2 ± 8.64, 32 cases), but the case fatality rate (56% vs.3.3% P <0.01) and the combined infection rate (87.5% vs.62.8%, P <0.05). In addition, the incidence of MODS was significantly different between the shock and non-shock groups, with and without infection (31.9% vs.18%, P <0.05; 38.9% vs.8%, P <0.001, respectively). The main injury site had no significant effect on MODS. Conclusion: The infection is still the most closely related to the occurrence of MODS after severe multiple trauma. In contrast, the importance of shock in inducing MODS has declined.