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目的分析影响胰头癌术后存活时间的相关因素。方法对南京医科大学附属南京第一医院1995~2004年收治的65例胰头癌的临床及病理因素行COX多元回归分析及单因素分析。结果分析显示肿瘤直径≥2cm、淋巴结转移、MVD(P<0·01)、uPA(P<0·01)是影响术后生存期的因素。COX多元回归分析uPA是决定预后的独立因素。结论多种因素影响胰头癌术后存活时间,其中胰头癌本身生物学特性起决定作用。
Objective To analyze the related factors that influence the postoperative survival time of pancreatic cancer. Methods The COX multiple regression analysis and univariate analysis were performed on the clinical and pathological factors of 65 patients with pancreatic head carcinoma admitted to Nanjing No.1 Hospital Affiliated to Nanjing Medical University from 1995 to 2004. The results showed that the tumor diameter ≥ 2cm, lymph node metastasis, MVD (P <0.01), uPA (P <0.01) were the factors influencing the postoperative survival. COX multiple regression analysis uPA is an independent factor in the prognosis. Conclusions Various factors affect the postoperative survival time of pancreatic cancer, and the biological characteristics of pancreatic cancer itself play a decisive role.