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目的为晚期胰腺癌的姑息治疗寻找新的方法。方法晚期胰腺癌２７例，在胆肠和（或）胃肠转流手术基础上行胰周动脉结扎及术中瘤体内注射无水酒精，观察生存期及症状缓解情况。结果２７例病人的临床症状均有不同程度缓解，瘤体内注射无水酒精者肿瘤缩小３０％以上；随访２４例，平均生存期９．４±２．１个月，较对照组（５．５±０．４个月）明显延长（Ｐ＜０．０１）。结论胰周动脉结扎及瘤体内注射无水酒精为晚期胰腺癌提供了一种新的、比较有效的治疗方法。
Objective To find new methods for palliative treatment of advanced pancreatic cancer. Methods Twenty-seven cases of advanced pancreatic cancer were treated with biliary artery ligation and intraoperative injection of absolute alcohol in the gallbladder and/or gastrointestinal bypass. The survival and symptom relief were observed. Results The clinical symptoms of 27 patients were all relieved to varying degrees. Tumors injected with absolute alcohol in vivo were reduced by more than 30%; 24 patients were followed up and the average survival time was 9.4±2.1 months, compared with the control group (5.5 ± 0.4 months) significantly prolonged (P <0.01). Conclusion Peripapillary artery ligation and intratumoral injection of absolute alcohol provide a new and more effective treatment for advanced pancreatic cancer.