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目的:探讨剖宫产术围手术期短程预防应用抗生素的有效性和可行性。方法:440例剖宫产产妇随机分为观察组和对照组各220例,观察组头孢噻肟钠2.0 g溶于100 ml生理盐水,手术前0.5 h开始静脉滴注,0.5 h滴完,手术时间超过3 h再给第2组;对照组,术后采用常规用药方案,回病房用头孢噻肟钠静脉滴注,连续3 d。结果:两组术后术后病率、产褥感染、切口感染等无明显差别(P>0.05)观察组子宫复旧不良、平均住院时间、术后住院时间低于对照组(P<0.05)。结论:剖宫产围手术期短程预防应用头孢噻肟钠预防术后感染是一种合理有效而又经济的方案。
Objective: To investigate the effectiveness and feasibility of perioperative short-term prophylaxis with antibiotics in cesarean section. Methods: Four hundred and forty-four cesarean section women were randomly divided into observation group and control group with 220 cases in each group. The observation group was dissolved 2.0 ml cefotaxime sodium in 100 ml normal saline, 0.5 hours before the operation, Time more than 3 h to give the second group; control group, after the use of conventional drug regimen, back to the ward with cefotaxime sodium intravenous infusion for 3 days. Results: The postoperative morbidity rate, puerperal infection and incision infection in the two groups showed no significant difference (P> 0.05). The uterus in the observation group had poor hospitalization, average length of hospital stay, and postoperative hospital stay less than those in the control group (P <0.05). Conclusion: Cesarean section perioperative short-term prevention of cefotaxime sodium to prevent postoperative infection is a reasonable and effective and economical solution.