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目的：探讨低剂量多巴酚丁胺负荷超声心动图（ＬＤＤＳＥ）和９９ｍ锝甲氧基异丁基异腈（９９ｍＴｃＭＩＢＩ）心肌显像对初发急性心肌梗死患者心室壁运动障碍自发性改善的预测价值。方法：２７例初发急性心肌梗死患者于发病后１周内行ＬＤＤＳＥ试验，并随访４个月后的心室壁运动。９例溶栓治疗患者行９９ｍＴｃＭＩＢＩ心肌显像。结果：９例溶栓治疗患者中，６例发生缺血再灌注，随访时心室壁运动障碍改善。未发生缺血再灌注的３例患者中，２例随访时心室壁运动障碍改善，１例恶化。ＬＤＤＳＥ试验对急性心肌梗死后心室壁运动障碍自发性改善预测的敏感性、特异性分别为７１％和８４％，阳性预测值和阴性预测值均为７８％。结论：ＬＤＤＳＥ试验对初发急性心肌梗死后心室壁运动障碍的自发性改善有较高的预测价值
Objective: To investigate the effects of low-dose dobutamine stress echocardiography (LDDSE) and 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) myocardial imaging on the improvement of spontaneous ventricular wall motion in patients with newly diagnosed acute myocardial infarction Predicted value. Methods: Twenty-seven patients with newly diagnosed acute myocardial infarction underwent LDDSE within one week after onset and were followed up for 4 months. 9 cases of thrombolytic therapy patients with 99mTcMIBI myocardial imaging. Results: Of the 9 patients treated with thrombolytic therapy, 6 developed ischemia-reperfusion and the improvement of ventricular wall motion disorder at follow-up. Of the 3 patients without ischemia-reperfusion injury, 2 showed improvement in ventricular dyskinesia and 1 deteriorated at follow-up. The sensitivity, specificity, and specificity of the LDDSE test for predicting spontaneous improvement of ventricular wall motion disorder after AMI were 71% and 84%, respectively, with a positive and negative predictive value of 78%. CONCLUSIONS: The LDDSE test has a high predictive value for spontaneous improvement of ventricular wall motion disorder after first-episode acute myocardial infarction