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一般临床上治疗心力衰竭的传统原则为,应用洋地黄类制剂以增强心肌收缩力,增加心排血量;应用利尿剂以减轻心脏负荷;控制盐与水的摄入以避免钠与水潴留。但以上的治疗原则对于慢性心力衰竭(下称慢性心衰)往往难以奏效,且容易发生洋地黄中毒。近几年国外广泛研究血管扩张剂与非洋地黄类正性收缩能药物对慢性心衰的治疗,取得了一些进展。现就临床上常用的上述两类药物对慢性心衰的治疗简介如下。
The general principle of clinical treatment of heart failure, the application of digitalis preparations to enhance myocardial contractility and increase cardiac output; use diuretics to reduce heart load; control of salt and water intake to avoid sodium and water retention. However, the above principles of treatment for chronic heart failure (hereinafter referred to as chronic heart failure) are often difficult to work, and prone to digitalis poisoning. In recent years, foreign extensive study of vasodilators and non-digitalis positive systolic drug treatment of chronic heart failure, and made some progress. Now commonly used clinically on the above two types of drugs on the treatment of chronic heart failure is as follows.