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铬是一种常见的环境污染毒物 ,铬主要通过呼吸道和皮肤进入机体 ,主要对肝、肾组织造成损害 ,而 6价铬的毒性高于 3价铬。肝肾组织中存在一种与铬特异性结合 ,分子量约为 150 0D的低分子铬结合物 (Lowmolecularweightchromiumbindingsubstance ,LMCr) 〔1〕。为研究生物标志物
Chromium is a common environmental pollutant. Chromium mainly enters the body through the respiratory tract and skin and mainly damages the liver and kidney tissues. The toxicity of hexavalent chromium is higher than that of trivalent chromium. In liver and kidney tissue there is a low molecular weight chromium conjugate (LMCr) with a specific molecular weight of about 150 0D which binds chromium [1]. To study biomarkers