An old patient with growing teratoma syndrome of the ovary

• 作 者: Sadiman Kiykac Altinbas Taner Turan Namik Kemal Altinbas Ahmet Ozfuttu Nurettin Boran Gokhan Tulunay
• 机 构: Etlik Zubeyde Hanim Women’s Health Teaching and Research Hospital, Department of Gynecology and 0bst
• 出 处: 亚太生殖杂志（英文版）
• 发表日期: 2013年2期
• 关键词: Growing teratoma syndrome Chemotherapy Immature teratoma Ovary

Growing teratoma syndrome (GTS) is a rare complication of malignant ovarian germ cell tumors. A 52-year old woman was admitted to our Gynecological Oncology Department with metastatic multiple abdominal masses. Her initial gynecological history presented an immature teratoma of the ovary 3 years previously, and she underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, bilateral pelvic-paraaortic lymphadenectomy and omentectomy. She received three cycles of bleomycin, etoposide and cisplatin (BEP) regimen after surgery. Although the tumor markers were within normal limits, multiple metastatic lesions were detected in the 3rd month of follow-up. The patient was referred to our gynecological oncology department, optimal debulking including resection of the tumoral lesions localized on the liver, diaphragm, peritoneum, sigmoid colon, omentum and retroperitoneum was performed. Histopathology of all samples revealed mature teratoma. This syndrome should be remembered when a tumor is refractory to chemotherapy and growth of the tumor still continues after resection of the initial tumor.