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矽肺作为我国最严重的一种职业病,主要分布于煤炭、冶金、有色金属、建工等工业系统,患者多为长期在粉尘环境中作业的老工人。该病除给患者带来很大痛苦外,还给国家造成了直接和间接的严重经济损失。随着我国经济体制改革的不断深入,尤其是乡镇企业的迅速发展,目前矽肺新病例呈逐年增长的趋势,使矽肺的防治工作越来越紧迫。研究开发高效低毒治疗矽肺的新药,是当前迫切需要完成的一项重要课题。
Silicosis, as one of the most serious occupational diseases in our country, is mainly distributed in industrial systems such as coal, metallurgy, non-ferrous metals and construction industry. Most of the patients are old workers who work in dusty environment for a long time. In addition to causing great suffering to patients, the disease has also caused direct and indirect serious economic losses to the country. With the continuous deepening of China’s economic reform and the rapid development of township and village enterprises, the number of new cases of silicosis has been increasing year by year, making the prevention and control of silicosis more and more urgent. Research and development of new drugs with high efficiency and low toxicity for the treatment of silicosis is an urgent issue that needs to be completed urgently.