论文部分内容阅读
通过1-苯基-3-三氟甲基-5-氯吡唑-4-甲酰氯(4)与α-羟基芳甲基膦酸酯(6)的缩合反应,合成了14种标题化合物7a～7n.所有化合物的结构均经1H NMR,IR和元素分析进行了表征,并且采用X射线单晶衍射分析方法进一步测定了化合物7j的结构.初步的生物活性测试表明,部分标题化合物具有一定的杀菌和除草活性.
Fourteen title compounds 7a were synthesized by the condensation reaction of 1-phenyl-3-trifluoromethyl-5-chloropyrazole-4-carbonyl chloride (4) and α-hydroxyarylmethyl phosphonate (6) ~ 7n.The structures of all the compounds were characterized by 1H NMR, IR and elemental analysis and the structure of compound 7j was further determined by X-ray single crystal diffraction analysis.The preliminary bioassay showed that some of the compounds had some Bactericidal and herbicidal activity.