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为检测增殖细胞核抗原（ＰＣＮＡ）在食管鳞癌的表达及其临床病理关系，对４９例手术切除的食管鳞癌标本，行免疫组化法检测单克隆抗体ｐｃ１０的表达。结果显示ＰＣＮＡ的表达强度与食管鳞癌的分化程度成反比，与有无淋巴结转移成正比，差异有显著性意义（Ｐ＜０．０５）；与肿瘤浸润深度无明显相关。提示ＰＣＮＡ的表达强度可反映食管鳞癌细胞增殖活力和转移能力
To detect the expression of proliferating cell nuclear antigen (PCNA) in esophageal squamous cell carcinoma and its clinicopathological relationship, immunohistochemical method was used to detect the expression of monoclonal antibody pc10 in 49 specimens of esophageal squamous carcinoma. The results showed that the expression intensity of PCNA was inversely proportional to the degree of differentiation of esophageal squamous cell carcinoma and proportional to the presence or absence of lymph node metastasis (P<0.05). There was no significant correlation with the depth of tumor invasion. It is suggested that the expression intensity of PCNA may reflect the proliferation activity and metastasis capacity of esophageal cancer cells